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Nausea affects 28% at the 12mg dose

Kung et al., 2008)

And it changes how success should be measured: not as "I lost the weight and stopped," but as "I am managing a chronic condition that requires ongoing treatment." How to think about GLP-1 therapy None of this means stopping is never appropriate

GLP-1 Receptor Agonist Medications vs

During the first year after treatment began, 27.0% of patients reduced their BMI by less than 5%, 22.4% lost between 5% and less than 10%, 14.1% lost between 10% and less than 15%, and 15.8% reduced BMI by at least 15%

Materials and methods Trial design and oversight The trial was a prospective, randomized, parallel group, placebo-controlled trial in women with active IIH