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Similarly, severe abdominal pain, particularly if localised to the upper abdomen and radiating to the back, requires urgent assessment to exclude pancreatitis, a rare but serious potential adverse effect of GLP-1 receptor agonists identified in the Wegovy SmPC and MHRA safety monitoring

Initial management included nasogastric decompression, intravenous fluids, bowel rest, and pain control

Why Semaglutide May Cause Temperature Sensitivity GLP-1 activation influences appetite centers in the hypothalamus, the brain region that also regulates core body temperature and thermoregulation

Diabetes (2012) 61:215565

Yet, while GLP1/E and GLP1/GIP reduced body weight by 10% at the end of the treatment, the triagonist caused a 22% reduction (Fig

Usually, these headaches are not very severe and pass quickly within a few days