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And alcohol deserves extra caution because GLP-1 medications can change how your body processes it

Pfizer terminated lotiglipron in October 2023 due to dose-dependent liver enzyme elevations, and subsequently discontinued danuglipron in April 2025 after a single case of potential drug-induced liver injury was identified in a dose-optimization study

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These agents have now been in patients for decades without major safety signals but as with any agent, further vigilance is required

We finally have a working answer to one of medicine's most argued nutrition questions: how much protein should your patients actually eat

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