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Two recent studies suggest that treating obesity and metabolic dysfunction with GLP-1 drugs could help restore hormonal balance and reproductive function in both women and men.

Mechanistic hypotheses include reduced leptin-driven T-helper (Th)1/Th17 activity, improved adipokine balance, and modulation of gut-thyroid axis pathways

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A major change to her prescription benefits meant the medication she was using to manage her weight - a treatment that had taken years of trial and error to get right - would no longer be covered by insurance.

Current expectations point to FDA review and potential approval in the 2027 to 2028 range