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In terms of ventricular load, SGLT2i reduce cardiac load via osmotic diuresis and enhance urinary sodium excretion while also decreasing arterial stiffness and improving endothelial function [109]

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Ideally data suggests both are underestimating something: this isn't a volume problem you can price or reassure your way through

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For employers, this is not just about one carriers move

The switch is not a simple 1:1 conversion dosing typically restarts at a lower level to reduce side effects, then titrates up