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It also lowered systolic blood pressure by 26 mmHg in hypertensive individuals and caused a modest increase in heart rate (24 beats/min), regardless of hypertension [30]

3d), sustained plasma Exe4 concentrations and therapeutic effects were observed in DIO mice, owing to the compensatory high gene expression at the Alb gene in hepatocytes

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McGovern A, Tippu Z, Hinton W et al

Mechanisms of Action and Therapeutic Applications of GLP-1 and Dual GIP/GLP-1 Receptor Agonists