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Int J Mol Sci 23(2):739 Mezza T, Cinti F, Cefalo CMA, Pontecorvi A, Kulkarni RN, Giaccari A (2019) -cell fate in human insulin resistance and type 2 diabetes: a perspective on islet plasticity

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Characterization of the molecular mechanisms underlying glucose stimulated insulin secretion from isolated pancreatic beta-cells using post-translational modification specific proteomics (PTMomics)

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Tirzepatide achieves 20.9% at 72 weeks on 15mg, per SURMOUNT-1 (Jastreboff et al., NEJM 2022)