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The American Society of Anesthesiologists (ASA) recommends withholding these drugs before surgery, but definitive guidelines remain unclear

Phentermine and GLP-1 receptor agonists are distinct medications that work through different biological pathways to support weight loss

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Initially designed for managing type 2 diabetes, these GLP-1 receptor agonists have proven so effective at curbing appetite that theyre now being prescribed off-label for weight loss

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Purpose of Review This review explores the role of GLP-1 receptor agonists (GLP-1 RAs) in addressing metabolic dysfunction and neurodegeneration in Parkinsons disease (PD), focusing on body weight regulation and neuroprotection