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2023aRetatrutide, a GIP, GLP-1 and glucagon receptor agonist, for people with type 2 diabetes: a randomised, double-blind, placebo and active-controlled, parallel-group, phase 2 trial conducted in the USA

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In patients with heart failure, insulin can actually worsen fluid retention and edema, making careful monitoring essential

It reduced the surface area of the lesions, lessened the plaque size and monocyte/macrophage accumulation

Alcohol use disorder (AUD) A random-effects meta-analysis of three studies [25,26,27] demonstrated that GLP-1RA use was associated with a significantly lower risk of AUD diagnosis compared with nonGLP-1RA comparators (HR = 0.72, 95% CI: 0.590.89, p = 0.0019)