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In a review of clinical trials, the combination of combined oral contraceptive pills (COCPs) with either a GLP-1RA or tirzepatide (GLP-1 and Glucose-dependent insulinotropic polypeptide (GIP) receptors agonist) did not affect the efficacy of contraceptive drugs, even though GLP-1RAs can decrease the absorption of the concomitantly administered drug through their gastric delaying effect

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Yes, but with important caveats

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Activating these receptors produces direct protective effects

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They dont demand more effortthey remove the urgency

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Harv Rev Psychiatry

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