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Encouraged by these results, Novo Nordisk launched the much larger SOUL trial the following year

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The second cohort (control group) contained patients with diagnosis of MASLD/MASH who did not receive a GLP-1 agonist

For IL-10, GE2 tended to reduce levels compared to vehicle-treated subjects (main effect of treatment: F (1,47) = 3.744, p 2 = 0.074, p = 0.059

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