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Measurements: The primary outcome was incident ION as a proxy for NAION

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In a 72-week study, people taking mounjaro 15mg lost about 22.5% of their starting weight, while 91% lost at least 5%

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This level of success is comparable to, or even exceeds, the outcomes seen with surgical interventions, making Tirzepatide a game-changer in medical weight loss

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At sub-therapeutic levels like 0.5 mg (10 units from a 5 mg/mL vial), receptor activation is minimal

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B12 is generally well-tolerated and does not affect gastric acid production or esophageal sphincter function

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