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Tirzepatide is also less effective at reducing body weight in T2D patients compared to patients without (15.7% weight loss, SURMOUNT-2 and 22.5% weight loss, SURMOUNT-1, respectively)

Asmar, A

Therefore, the cause of the emergence of gastrointestinal distress after taking metformin may also be related to mutations in the patients drug transporter protein genes

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Addressing the implications of GLP-1 medications through informed consent and thorough patient education ensures that patients understand the potential risks and are better prepared to manage their health effectively

10.1038/nrc2694 34 WangY