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Ida S, et al
Never discontinue prescribed diabetes medications without medical supervision, as abrupt changes can lead to dangerous glucose fluctuations

J Diabetes Investig 1:823 Samms RJ, Coghlan MP, Sloop KW (2020) How may gip enhance the therapeutic efficacy of GLP-1

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Evidence demonstrates that acute glucose fluctuation forms the stress that alters microglial activity (eg, inflammatory activation or self-degradation), which may be one of the mechanisms of cognitive deterioration in diabetic patients
