glp 1 agonist with dpp 4 inhibitor DPP-4 inhibitors and GLP-1RAs: cardiovascular safety and benefits | Military Medical Research do not combine dpp-4 inhibitors

Ferrannini E, Mark M, Mayoux E

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We first reported that the internalization of GLP-1 is compromised in the presence of GIPR full agonist IUB68 (22)

1998 Jun;42(6):886891

The question has gained visibility due to anecdotal accounts of so-called Ozempic babies. This paper aims to delineate mechanisms linking GLP-1 receptor activation with reproductive outcomes, review clinical data on fertility, and outline implications for practice

23 Adverse reactions and tolerability: The DPP-4 inhibitor class of medications is generally very well tolerated, although post-marketing reports have described serious adverse events (see Warnings and precautions section)