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However, the initial findings are promising
GISSI-Prevenzione, Investigators

Conceptually, this could be a reversal of dysfunction in established diabetes or a prevention of dysfunction in new onset diabetes (operationally defined as starting within one week after start of diabetes)

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In the only head-to-head that exists, tirzepatide was slightly better tolerated than semaglutide

Animal studies have shown potential risks to fetal development, and there is insufficient human data to determine safety
