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doi: 10.1210/jc.2019-01262

The 2.4mg weekly dose produced an average 14.9% body weight reduction at 68 weeks in participants with obesity, a number that at the time seemed extraordinary

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A study published in Biology analyzing GLP-1 receptor signaling found elevated reporting odds ratios for dry mouth across the entire drug class, with tirzepatide showing a ratio of 1.35