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Diabetes Obes Metab 19(3):33647 [DOI] [PubMed] [Google Scholar] Buse JB, Klonoff DC, Nielsen LL, Guan X, Bowlus CL, Holcombe JH et al (2007) Metabolic effects of two years of exenatide treatment on diabetes, obesity, and hepatic biomarkers in patients with type 2 diabetes: An interim analysis of data from the open-label, uncontrolled extension of three double-blind, placebo-controlled trials

However, after losing weight, he stopped using the GLP-1 and told People that he quickly regained 20 pounds

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Retatrutide vs tirzepatide The comparison with tirzepatide is more nuanced because tirzepatide already targets two receptors (GLP-1 and GIP)

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