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In the longer-term trials that reported individual adverse event categories associated with discontinuation of drug treatment, nausea was shown to be the leading cause of discontinuation, followed by vomiting and diarrhea, with much lower risks associated with constipation, abdominal discomfort, or pain (Table 3)
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Scand J Gastroenterol
When a cytokine binds to its corresponding receptor, the receptor-associated JAK is activated
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