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c Participants with major depressive disorder or generalized anxiety disorder whose disease state is considered stable for the past 2 years and expected to remain stable throughout the course of the study, in the opinion of the investigator, may be considered for inclusion if they are not on excluded medications

In retatrutide trials specifically, starting at 4 mg instead of 2 mg nearly doubled early GI symptom rates

The broader peptide regulation landscape is evolving rapidly

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