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Thirdly, the COVID-19 pandemic significantly impacted the study, with the majority of participants either randomised just before the pandemic or reaching the critical 6 month and 12-month trial milestones during the pandemic

The rapid drop in weeks 1 to 2 is largely water and glycogen, not fat

To minimise any potential effect, patients should continue taking levothyroxine as directedtypically 3060 minutes before breakfast on an empty stomachand maintain consistent timing

MTC is a rare form of thyroid cancer originating from parafollicular C-cells, accounting for approximately 3-4% of all thyroid malignancies

(2021) 22(Suppl 4):e13239

Biologia 75:20632071 Thiry A, Dogne J-M, Supuran CT, Masereel B (2008) Anticonvulsant sulfonamides/sulfamates/sulfamides with carbonic anhydrase inhibitory activity: drug design and mechanism of action