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However, new research has found that up to one in 10 people may have genetic variants that make them resistant to the effects of these drugs

This is particularly important, considering that Pfizer NYSE: PFE recently discontinued its oral GLP-1 treatment because of these issues

There was no significant difference in patient outcome with the type of GLP-1RA, nor with recent or more distant exposure to these drugs

Biochem J (1980) 187(2):33743

The weight loss effects were discovered as a beneficial side effect, and many doctors now prescribe it off-label for weight management

The supplements are thought to have an anti-inflammatory effect