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Pharmacokinetics: Bioavailability: ~90% Half-life: ~2430 hours Metabolism: Minimal hepatic metabolism Excretion: Mainly renal Adverse Effects: Headache Nausea Abdominal pain Diarrhea Interesting Fact: Unlike older prokinetic agents (like cisapride), prucalopride has high receptor selectivity, reducing the risk of cardiac arrhythmias a major safety improvement

Weight struggles and metabolic issues can lead to feelings of frustration, low self-esteem, and depression

Patients are usually instructed to attach a new sterile needle for each injection

Because Qsymia carries a boxed warning for birth defects, patients who can become pregnant need a negative pregnancy test before starting, monthly tests during therapy, and effective contraception

The vast majority of people should use standard bacteriostatic water

Similarly, Pendulums GLP-1 Probiotic is marketed as being able to naturally curb cravings with their probiotic blend, but research from the American Diabetes Association suggests that Pendulums probiotic blends should only be used as an add-on rather than as a primary treatment until more robust data is available