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Fatigue is an issue when using Mounjaro as it can lead to fluctuating energy levels due to reduced calorie intake
That trial, called SURPASS-CVOT, will finish in mid-2025 and could really give us the details we need to see how effective tirzepatide is in reducing heart disease, he says
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Decreased appetite, fatigue, and headaches are also common
The SELECT trial (NEJM, 2023) demonstrated that semaglutide 2.4mg reduced major adverse cardiovascular events (MACE) by 20% in over 17,000 patients with overweight/obesity and established cardiovascular disease, without diabetes
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