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Description
These delays highlight the structural barriers that can slow adoption in populations with higher rates of comorbidities

The search strategy incorporated terms related to GLP-1 receptor agonists (e.g., GLP-1, Semaglutide, Liraglutide, Exenatide) in combination with alcohol use concepts (e.g., alcohol, alcohol use disorder, binge drinking, ethanol)

Retatrutide's 6-day half-life means it takes 4-5 weeks to reach steady-state levels at each dose, which is why the standard protocol uses gradual 4-week escalation intervals

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Once youve completed pregnancy (and breastfeeding, if applicable), your provider can help you safely resume treatment if appropriate
