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The agency will continue to work with state regulators, monitor the market, and take enforcement actions as necessary to prevent unsafe or fraudulent GLP-1 drugs from reaching U.S

This graph diagrams utilization, unit cost, and cost as a percent of overall medical cost trend: note that by the middle of 2023, GLP-1 drug costs for Group health plan members comprised 13.6% of a major pharmacy benefit management (PBM) company, shown in the third bar

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Results Compared with D&E, semaglutide 2.4 mg in combination with D&E generated an additional 0.1049 QALYs and a 2685 increase in costs over 40 years, resulting in an incremental cost-effectiveness ratio of 25,589/QALY