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Keywords: type 2 diabetes, DPP-4 inhibitors, oral antidiabetic, incretin-based therapy, gliptin, combination therapy Introduction The regulation of insulin secretion is important to maintain euglycaemia

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Clinical trial data found that people using 5-mg injections of tirzepatide lost about 15% of their weight after more than a year of treatment, on average

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The GDF-15 RA use as a potential treatment for obesity stems from observations that elevated tumour-secreted GDF-15 is correlated with WL [99]