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Factors like prior experience, overall health, and tolerance are part of the decision-making process

Cardiovascular and renal outcomes with canagliflozin according to baseline kidney function

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The majority of physicians have been in practice for more than 10 years: 13 percent practiced for fewer than 10 years, while 40 percent practiced for 10 to 19 years, 34 percent for 20 to 29 years, and 12 percent for more than 30 years
The longer-term safety profile of retatrutide is unclear

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