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This mostly modulates GLP-1 homeostasis through the action of a GLP-1 receptor agonist [31]

McGowan said two other side effects among study participants urinary tract infections and dysesthesia, or a painful burning sensation to touch had not previously been linked to weight-loss medications

These two receptor systems overlap in some functions and diverge in others

(PDF) Schettino M*, Dan R*, Parrillo C, Giove F, Napolitano A, Ottaviani C, Pizzagalli DA (2025)

And if you are dealing with acid reflux as a concurrent side effect, avoid large water volumes immediately before or during meals, as this can worsen reflux symptoms while your gastric emptying is already delayed

The efficacy of GLP-1s has made them a breakthrough not only in managing obesity and diabetes, but also in their potential to treat several related conditions