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The modified Rankin Scale (mRS) at 90 days was missing for 3 (4.3%) patients in the semaglutide group and 2 (2.8%) patients in the standard therapy group due to loss to follow-up (Table S2)

The first draft of the manuscript was written by AO and HY, and all authors commented on previous versions of the manuscript

Moreover, we noted the influence of publication bias in some studies, suggesting a potential bias in the journals selection of articles for publication

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Yes, they do, but clinical trials do not recruit millions of participants