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10.1128/mbio.02032-23 mBio

[DOI] [PubMed] [Google Scholar] 37.Drucker D.J., Buse J.B., Taylor K., Kendall D.M., Trautmann M., Zhuang D., Porter L., DURATION-1 Study Group Exenatide once weekly versus twice daily for the treatment of type 2 diabetes: A randomised, open-label, non-inferiority study

The FDA states that compounded drugs are "not reviewed by FDA prior to marketing and are not FDA-approved." What this means for consumers: When accessing compounded semaglutide or tirzepatide through telehealth platforms, you are receiving a medication that contains the same active ingredient as FDA-approved products but is prepared differently and has not undergone FDA approval as a finished product

Not every insurance plan includes benefits for GLP-1 medications or physician-guided medical weight loss

Importantly, despite the evidence for use of SGLT-2 inhibitors for DKD treatment, they should not be used in patients with type 1 diabetes because of the risk of euglycaemic diabetic ketoacidosis

Certain cancers While more research is needed, GLP-1s are associated with a lower risk of certain cancers, according to studies