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"Phentermine is a more cost-effective alternative and an option for people who would benefit from modest weight loss, do not have coverage for semaglutide, or do not want to take an injectable medication," says Kushner.

The neuroscience community has long grappled with finding effective, targeted medications for stimulant use disorders, owing to the complex neural adaptations cocaine elicits

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Acute administration of semaglutide, tirzepatide, and retatrutide each dose-dependently attenuated alcohol discrimination, suggesting that blunting or altering subjective alcohol effects could be a common target of this drug class

For thyroid patients, understanding your genetic profile may help your provider anticipate whether more conservative dosing or closer monitoring is warranted

Pregnant women or those planning pregnancy should avoid both GLP-1 medications and alcohol