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Diabetes drugs Taking metformin, a commonly prescribed oral antidiabetic drug and topiramate may increase the risk of side effects of both medications, including metabolic acidosis (a condition in which the fluids in your body have too much acid)

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Front Endocrinol (Lausanne) 13:1033479

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2.5 Statistical analysis To enable pooled analysis, scores from both the YFAS and mYFAS 2.0 were analyzed as change from baseline instead of absolute change