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Though the effect rarely makes headlines, it could prevent devastating diabetes-related health problems for millions, says Louis J

They exert direct protective effects on blood vessels , reducing inflammation and improving endothelial function [5, 6]

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GLP-1 Medications and IBS Symptom Overlap Common side effects of GLP-1 therapynausea, constipation, diarrhea, and abdominal discomfortcan mimic or worsen existing IBS symptoms, making it difficult to distinguish between medication effects and disease activity

Use In Specific Populations 8.1 Pregnancy Risk Summary Based on animal data showing adverse renal effects, XIGDUO XR is not recommended during the second and third trimesters of pregnancy