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The key finding was that plasma concentrations in patients taking 8 mg of retatrutide (approximately 182 nanomolar) exceeded the effective concentrations observed in the laboratory, suggesting these cardiac effects are clinically relevant at therapeutic doses

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[DOI] [PMC free article] [PubMed] [Google Scholar] 25.Glucagon-like peptide 1 analogue therapy directly modulates innate immune-mediated inflammation in individuals with type 2 diabetes mellitus

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[DOI] [PMC free article] [PubMed] [Google Scholar] 199.Wong C.K., McLean B.A., Baggio L.L., Koehler J.A., Hammoud R., Rittig N., Yabut J.M., Seeley R.J., Brown T.J., Drucker D.J