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1,2,3 A recent single-center study demonstrated a 4.28-fold (95% CI, 1.62-11.29) increased risk of NAION with semaglutide, a glucagonlike peptide-1 receptor agonist (GLP-1RA), relative to nonGLP-1RAs

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Elon Musks Experience with Semaglutide Elon Musk has publicly credited his weight loss to a combination of fasting, exercise, and Semaglutide

However, insomnia is not listed as a common adverse effect in clinical trials or regulatory documentation

Your healthcare team can discuss whether switching to an alternative agent or trying a different class of diabetes medication (such as SGLT2 inhibitors or DPP-4 inhibitors) might be appropriate for your individual circumstances, in line with NICE guidance

These medications work through distinct mechanisms to increase intestinal fluid secretion and accelerate transit