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Direct-to-consumer prescription companies like Hims & Hers (public) and Ro (Series E) have expanded their offerings to include GLP-1s amidst rising popularity of the drugs

Semaglutide is an FDA-approved medication for obesity and diabetes that helps people lose about 15% of their weight when combined with lifestyle changes

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Diabetic patients treated with semaglutide (Ozempic) showed dose-dependent weight loss with an average ~6 kg at a 2 mg dose with 40% of patients losing more than 10% of their weight (1)

In rabbits and cynomolgus monkeys administered semaglutide during organogenesis, early pregnancy losses and structural abnormalities were observed at below the MRHD (rabbit) and 5-fold or greater the MRHD (monkey)