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Therefore, the activation of the IGF-2/IGF-1R axis may contribute to -cell survival in response to GLP-1, and importantly, the increased IGF-2 secretion may be essential for triggering this response, as also observed in embryonic development (41)

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Viking Theraputics: The GLP-1 start-up If you are a real risk-taker, Viking Theraputics (NASDAQ: VKTX) is a money-losing pharma start-up with GLP-1 drugs in clinical trials

This finding suggests a mechanism by which these drugs might reduce drinking: if alcohol feels less rewarding, motivation to consume it decreases

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