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For example, a meta-analysis of 45 randomized controlled trials observed a trend toward increased risk of thyroid dysfunction in patients treated with GLP-1 receptor agonists, although the findings did not reach statistical significance
Ethics declarations Competing interests All authors are employees and shareholders of Regeneron Pharmaceuticals, Inc., or were employees and shareholders at the time the studies were conducted

For a full list of side effects for these medications, visit the manufacturers website or look at the packaging insert

Hair loss and other long-term side effects One concern that surfaces with extended tirzepatide use is hair loss

Obesity increases cardiovascular risks (27) and causes adverse cardiac remodeling (28)
