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Specifically, Rybelsus enhances glucose-dependent insulin secretion from pancreatic beta cells, meaning insulin is released only when blood glucose levels are elevated

These actions go beyond glycemic control, positioning them as potential therapeutic agents for diseases in which inflammation plays a central pathogenic role (Drucker 2018)

Mortality in HICs has declined significantly over the past two decades, with current estimates between 1520%, yet the economic burden remains substantial, with per-patient costs ranging from $20,000 to $50,000 (2, 3)

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Consequently, choosing anti-hyperglycemic therapies with proven cardiovascular and renal benefits is now a cornerstone of T2DM management [2]