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Mean Difference, Standardized Mean Difference (SMD), and Their Use in Meta-Analysis: As Simple as It Gets
Connor, J

Think still the baseline should at least mention lifestyle interventions - serious, professionally supported changes (and not just the half - accusational "you should move more") as the leading therapeutic intervention

Endocrinology (2000) 141:94752

Reduces major adverse cardiovascular events via direct cardiac and endothelial receptor signalling

Additionally, Lorcaserin has been found to rely on preproglucagon (PPG) neurons in the NTS (PPG NTS ) to mediate its therapeutic effects on reducing food intake as demonstrated by the lack of response in mice in which PPG NTS neurons are ablated [136]
