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Kasyanov E, Pinakhina D, Rakitko A, Vergasova E, Yermakovich D, Rukavishnikov G, et al

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Ozempic mimics the effects of GLP-1, which plays a key role in regulating blood sugar and appetite

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All doses of cagrilintide resulted in greater weight loss than placebo, while 4.5 mg cagrilintide outperformed liraglutide

The findings support the concept of ghrelin resistance and suggest that dysregulation of this hormonal axis may contribute to persistent restrictive eating behaviours and impaired weight recovery