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Use With Caution in Research Contexts Because Tirzepatide interacts with GLP-1 and GIP receptor pathways involved in appetite regulation, glucose signaling, digestion, and metabolic function, additional caution may be warranted in research models involving significant metabolic, gastrointestinal, pancreatic, or endocrine-related conditions

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Steady-state blood levels require approximately 5 to 6 weeks of daily dosing to establish