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Performance on impairment testing varies according to both the dose and the route of administration, and the timing of peak impairment differs with each dosing regimen

The FDA label specifically warns against this

For weight loss purposes, combining semaglutide with a healthy diet and regular exercise can enhance the results

doi: 10.1007/S11739-016-1583-7

Most importantly, insulin-mediated glucose control is critical for the gutbrain axis because glucose is the irreplaceable source of energy in brain