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[DOI] [PMC free article] [PubMed] [Google Scholar] 17.Holman R.R., Bethel M.A., Mentz R.J., Thompson V.P., Lokhnygina Y., Buse J.B., Chan J.C., Choi J., Gustavson S.M., Iqbal N., et al

At lower starting doses the effect may not last a full 7 days but as your dose increases through titration, appetite control becomes more consistent across the week

Seek urgent care if you develop: Severe one-sided flank or back pain that comes in waves and will not settle Visible blood in your urine, or urine that turns pink, red, or brown Fever or chills with the pain a possible sign of an infected, blocked kidney Vomiting so persistent that you cannot keep any fluids down Frequently Asked Questions Do GLP-1 drugs like Ozempic cause kidney stones

Footnotes When appropriate and available

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Distinguishing tachyphylaxis from other explanations requires systematic evaluation