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Is long-term GLP-1 therapy safe for weight management

Semaglutide 2.4 mg (Wegovy) : For adults with at least one weight-related comorbidity and a BMI of at least 35 kg/m (or at least 30 kg/m in exceptional circumstances)

Diverse brain myeloid expression profiles reveal distinct microglial activation states and aspects of Alzheimers disease not evident in mouse models

furthermore, the risk increases with longer treatment durations, higher doses, and when these agents are used for weight loss

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