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In head-to-head trials, Tirzepatide outperformed existing GLP-1 receptor agonists such as semaglutide in reducing HbA1c and body weight

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Because of the unknown potential for serious adverse reactions in the breastfed infant due to the possible accumulation of SNAC, an absorption enhancer for Wegovy tablets, and because there are alternative formulations of semaglutide that do not contain SNAC that can be used during lactation, advise patients that breastfeeding is not recommended during treatment with Wegovy tablets

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What makes this especially intriguing is that GLP1 effects may extend to other hedonic drives, such as highcalorie eating, hinting at shared neural circuitry