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IBRO Neurosci Rep

Microdose tirzepatide uses a lower-dose version of that dual-pathway strategy

5 : e583

Salas Whalen puts it very directly

Its action on these three receptors suggests a complementary mechanism where glucagon-induced gluconeogenesis is inhibited by GLP-1/GIP, and glucagons enhancement of energy expenditure is augmented by the appetite-suppressing effects of GLP-1/GIP, thereby promoting weight loss [112]

[DOI] [PMC free article] [PubMed] [Google Scholar] 32.Liu T.M., Ling Y., Woyach J.A., Beckwith K., Yeh Y.Y., Hertlein E., Zhang X., Lehman A., Awan F., Jones J.A., et al
