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This means it could also potentially positively impact heart disease risk factors such as high blood pressure and high cholesterol

Risk: Novo has been steadily losing ground to Mounjaro and Zepbound, and Jim Cramer recently noted Lillys pipeline could deliver the unassailable knockout punch against Novo Nordisk because its got fat busting without muscle crunch. A value trap is the obvious failure mode

Inflammation and fibrosis can affect tubulo-interstitial lesions, and both glomerular and interstitial injuries will development of CKD

Am J Physiol Regul Integr Comp Physiol 2000

Zaccardi F, Htike ZZ, Webb DR, Khunti K, Davies MJ

Direct Stimulation of GLP-1 Receptors in the Brain: GLP-1 receptors are found in various areas of the brain, particularly those involved in appetite control and the sensation of nausea