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GLP-1 and lung injury (cytokine storm, surfactant production, and long term fibrosis formation) A study on a mouse model to evaluate the effect of GLP-1 analogs on ALI and ARDS caused by influenza virus showed that GLP-1 analogs do not affect viral particles, but could reduce the mortality rate among infected mice by inhibiting inflammatory pathways and cytokines such as IL-1, IL-6, and TNF- [75]

However, because these medications are not designed to directly induce ovulation, a "washout period" is typically recommended before attempting to conceive

An off-label use means that the medication is not officially approved to treat that specific condition

Special Populations: Seniors and Age-Related Considerations Adults aged 65 and older can safely use GLP-1 medications including semaglutide, though dose adjustments and kidney function monitoring become increasingly important with advancing age